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Systemic AL (kappa type) Amyloidosis involving liver and bone marrow, heart, lung
Seul Han1 , Se eun Kim2, Mee Yon Cho3, Ji whan Moon3, Moon young Kim1
1Division of Gastroenterology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, wonju, Korea
2Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju college of Medicine, Wonju, Korea
3Department of Pathology, Yonsei University Wonju College of Medicine, wonju , Korea
Address for Correspondence:  Seul Han ,Tel: 033-741-1229, Fax: 82-10-741-0951, Email: lolhsk@yonsei.ac.kr
Received: 17 April 2024;  Accepted: 27 May 2024.  Published online: 27 May 2024.
ABSTRACT
Systemic amyloidosis is characterized by the accumulation of insoluble proteins in tissues including heart, kidney, liver and any other organs. Light chain amyloidosis is the most common type of primary amyloidosis. And it is generally considered to be accompanied by plasma cell dysfunction. Given its pathogenesis, it may affect any organ system. Thus, clinical presentation can be variable and diagnosis can be delayed. Here, we presented a systemic amyloidosis presented as liver dysfunction without any specific symptoms.
Keywords: Amyloidosis; Liver diseases; Immunoglobulin Light-chain Amyloidosis; Plasma Cells
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Systemic Light Chain (Kappa Type) Amyloidosis Involving Liver and Bone Marrow, Heart, Lung  2024 May;9(1)
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